My original tumblr post was here. This image was first posted on tumblr by johnnythehorse, who attributes it to an Italian comic book called Vipera Bionda. A check at ComicVine indicates that this is indeed the cover of Vipera Bionda #17, first published November 17, 1978.:
The cover is the work of prolific Italian comics artist Emanuele Taglietti.
Reminds me of the 1978 film Coma, and the 1977 novel its based on.
Me too, and given the dating on this issue of Vipera Bionda it seems entirely possible that the art concept was straight-up swiped by Taglietti, or possibly by his editors who just asked him for “qualcosa di simile a Coma.”