You wouldn’t know it from this photo, but the role of the enormous bloody deformed conehead zombie creature is to save the nude lady from an evil mad scientist:
Two different blog posts assure us that this is a publicity photo (no such scene actually appearing in the movie) for the 1962 mad science horror flick The Brain That Would Not Die:
The movie itself is in the public domain and is viewable at the Internet Archive. More information about the film, including a detailed synopsis of the plot, is available at Wikipedia.
The monster-conehead-zombie was played by Eddie Carmel, a 7-foot, 3-inch tall giant known as “The Jewish Giant”. One website about him offers a tiny and watermarked version of this photo that has been cropped less than any of the others available on the web. (Although the clothing and bodies below the “Giants And Girls” legend appear crudely Photoshopped-in, the model’s belly button looks possibly original, indicating that there’s just a smidge more of the original photo in this version.)
This image is a reblog from a 10 November 2013 post at Infernal Wonders. Its original source is the long gone and greatly missed tumblr The World Of Doctor Orloff! (A very incomplete copy may be viewed in the Internet Archive.)