Very early (1933 — note the National Recovery Administration eagle ensign on the cover) variant on the tube-girl meme. Neither mad science nor meant literally in this context (I think) but still possibly something that inspired the imaginations of coming pulp artists.
Found at Drake’s Way.
the lurid colors certainly grab your attention. is she the spawn of the spider, or has she been caught in the web? I reach in my pocket for a dime, because I want to find out!!